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  • Writer's pictureLiza Klassen

Estrobolome (es - tro - bow - lom)

The estrobolome is a subset of the gut microbiome – it includes bacteria that produce an enzyme called beta-glucuronidase. Beta-glucuronidase has the ability to turn estrogen from it’s inactive (thanks to the liver) back into it’s active form. This active estrogen can now act on target tissues (think breasts, uterus, bone) and exert it's physiological effects.

The more of this bacteria we have populating our gut, the more beta-glucuronidase that is secreted, and the more active estrogen there is in circulation. Common symptoms/syndromes associated with this "high estrogen state" include;



-Heavy periods

-Fibrocystic breasts (think painful/lumpy or ropey breast tissue premenstrually)


-Pre-menstural headaches

Okay, but how do we know this is because of an overgrowth of bacteria and not another cause of high estrogen? Well, it's also associated with digestive symptoms like constipation/diarrhea, bloating, foul gas, indigestion, fatigue, brain fog....

SO, if you find yourself experiencing any of the hormonal symptoms listed above AND gut symptoms it's time to look into supporting your estrogen metabolism and gut microbiome. And lucky for you, I have 4 simple steps that you can start taking TODAY to move you towards a healthy gut and happy hormones.

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